David Cook,Robert Falotico,Lily Kuo,Jonathon Z. Zhao
申请号：
US11493324
公开号：
US08506984B2
申请日:
2006.07.26
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organisms reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic agents or compounds may also further reduce a biological organisms reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the prevention of thrombosis. The drugs, agents, and/or compounds may also be utilized to treat specific disorders, including vulnerable plaque. Implantable coated medical devices may be processed through annealing to better control the elution characteristics of the therapeutic agents. Furthermore, annealing leads to better therapeutic agent stability and a larger device shelf-life.
