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Cariprazine, optionally in the form of a salt, including cariprazine hydrochloride
专利权人:
RICHTER GEDEON NYRT.
发明人:
申请号:
NL300913
公开号:
NL300913I2
申请日:
2017.11.17
申请国别(地区):
NL
年份:
2017
代理人:
摘要:
The present invention relates to new D3 and D2 dopamine receptor subtype preferring ligands of formula (I): wherein R1 and R2 represent independently a substituent selected from hydrogen, alkyl, aryl, cycloalkyl, aroyl, or R1 and R2 may form a heterocyclic ring with the adjacent nitrogen atom; X represents an oxygen or sulphur atom; n is an integer of from 1 to 2, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates thereof, to the processes for producing the same, to pharmaceutical compositions containing the same and to their use in therapy and/or prevention of a condition which requires modulation of dopamine receptors.
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