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(THIO)CARBAMOYL-CYCLOHEXANE DERIVATIVES AS D3/D2 RECEPTOR ANTAGONISTS
专利权人:
RICHTER GEDEON NYRT.
发明人:
AGAINE CSONGOR EVA,GALAMBOS JANOS,NOGRADI KATALIN,VAGO ISTVAN,GYERTYAN ISTVAN,KISS BELA,LASZLOVSZKY ISTVAN,LASZY JUDIT,SAGHY KATALIN
申请号:
SI200431919
公开号:
SI1663996T1
申请日:
2004.05.21
申请国别(地区):
SI
年份:
2012
代理人:
摘要:
The present invention relates to new D3 and D2 dopamine receptor subtype preferring ligands of formula (I): wherein R1 and R2 represent independently a substituent selected from hydrogen, alkyl, aryl, cycloalkyl, aroyl, or R1 and R2 may form a heterocyclic ring with the adjacent nitrogen atom X represents an oxygen or sulphur atom n is an integer of from 1 to 2, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates thereof, to the processes for producing the same, to pharmaceutical compositions containing the same and to their use in therapy and/or prevention of a condition which requires modulation of dopamine receptors.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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