A system assists users in time and frequency analysis of magnetoencephalography (MEG) signals. In one aspect, a system includes an analysis module, a configuration module and a user interface. The analysis module performs a time and frequency analysis of the MEG signal, for example a short time Fourier transform (STFT) or a continuous wavelet transform (CWT) analysis. The analysis is parameterized by a parameter set that affects the time and frequency resolution of the analysis, for example window size and overlap size for STFT or center frequency and decay parameter for CWT. The configuration module automatically determines or assists the user to determine correct values for the parameter set.