The Board of Trustees of the Leland Stanford Junior University
发明人:
Michael Sano,Lei Xing
申请号：
US16781911
公开号：
US20200171303A1
申请日:
2020.02.04
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A ratio of reversible electroporation and irreversible electroporation may be controlled by selecting a symmetric waveform or asymmetric waveform to either minimize or enhance irreversible effects on cells in the target tissue. Combined reversible and irreversible electroporation includes inserting one or more therapeutic electrodes into a target tissue, introducing an electroporation compound into the target tissue, selecting a pulse waveform that is either 1) asymmetric bipolar that has positive and negative pulses with different durations, or 2) symmetric bipolar that has positive and negative pulses with the same duration, and delivering to the target tissue a series of electrical pulses having the selected pulse waveform.
