Kim, Hyun Uk,Lim, Hyung Kyu,Jang, Myung Hyun,Kim, Sang Yun,Bae, Sung Min,Kwon, Se Chang
申请号:
NZ70810313
公开号:
NZ708103A
申请日:
2013.11.06
申请国别(地区):
NZ
年份:
2018
代理人:
摘要:
A liquid formulation of a long-lasting oxyntomodulin derivative conjugate, comprising: a pharmacologically active amount of a long-lasting oxyntomodulin derivative conjugate, wherein the oxyntomodulin derivative conjugate comprises an oxyntomodulin derivative, which is a physiologically active peptide, comprising the amino acid sequence of SEQ ID NO: 24; an immunoglobulin Fc region; and a non-peptidyl polymer, wherein the non-peptidyl polymer covalently links the oxyntomodulin derivative and the immunoglobulin Fc region; and an albumin-free stabilizer, wherein the stabilizer contains a buffer, a sugar alcohol and a nonionic surfactant.