The present invention relates to an ophthalmological vehicle system for the permeation and/or for the active substance transport of ophthalmological active substances through the cornea and/or the sclera of the eye of mammals. This vehicle system assists the transport of the active substances through the cornea and/or the sclerotic tissue of the eye. The vehicle system is suitable for the prophylaxis and/or treatment of diseases of the front and/or back portion of the eye. Likewise, the present invention relates to an ophthalmological kit, comprising a special ophthalmological composition and also, as separate formulation, an ophthalmological active substance. In addition, the use of a special ophthalmological composition as vehicle system, penetration accelerator, penetration enhancer, absorption enhancer/-improver/-accelerator for the permeation and/or for the active substance transport of ophthalmological active substances through the cornea and/or the sclera of the eye of mammals is the subject of the invention. Furthermore, the invention relates to a fluid dispenser which comprises an ophthalmological vehicle system according to the invention.