A topical composition comprising at least 10 isolated active agents which eachhave at least one activity selectedfrom the group consisting of anti-oxidant activity, anti-matrixmetalloproteinase (MPP) activity, anti-elastase activity,anti-inflammation activity, anti-irritation activity, microcirculation supportactivity, collagen synthesis activity, energy production activity,oxygenation activity, DNA protection and repair activity, cell anchoragesuppport activity, dermal-epidermal cohesion supportactivity, cellular renewal activity, synthesis and/or protection ofglycosaminoglycans activity, prevention and/or repair and/orelimination of damaged proteins activity, protection of skin immune functionactivity, hydration activity, modulation of skinpigmentation activity, and anti-cellulite activity, the composition possessingat least five of the foregoing activitie. Methods of use thereof.
