НАЗАЛЬНЫЕ ТЕСТОСТЕРОНОВЫЕ ГЕЛИ С КОНТРОЛИРУЕМЫМ ВЫСВОБОЖДЕНИЕМ, СПОСОБЫ ПЕРНАЗАЛЬНОГО ВВЕДЕНИЯ И ПРЕДВАРИТЕЛЬНО ЗАПОЛНЕННЫЕ МНОГОДОЗНЫЕ АППЛИКАТОРНЫЕ СИСТЕМЫ ДЛЯ ПЕРНАЗАЛЬНОГО ВВЕДЕНИЯ
the present invention relates to \u0438\u043d\u0442\u0440\u0430\u043d\u0430\u0437\u0430\u043b\u044c\u043d\u044b\u043c \u0442\u0435\u0441\u0442\u043e\u0441\u0442\u0435\u0440\u043e\u043d\u043e\u0432\u044b\u043c \u0433\u0435\u043b\u044f\u043c for controlled release of testosterone in the bloodstream of male and female securing permanent effective levels of testosterone in the blood, causing undesired surges of testosterone in the blood after \u043f\u0435\u0440\u043d\u0430\u0437\u0430\u043b\u044c\u043d\u043e the introduction.\u0438\u043d\u0442\u0440\u0430\u043d\u0430\u0437\u0430\u043b\u044c\u043d\u044b\u0435 it gels according to this invention are safe, easy to use, well tolerated, are stable and can be easily and were reproduced \u0432\u043e\u0434\u0438\u043c\u043e to up scale.in addition, as it is considered that testosterone levels above normal and below normal presumably reduced essentially to minimize or \u0438\u0437\u0431\u0435\u0433\u0430\u044e\u0442\u0441\u044f and levels testosterone in serum and allegedly remained essentially constant during the period of 2 doses).according to the present invention \u0438\u043d\u0442\u0440\u0430\u043d\u0430\u0437\u0430\u043b\u044c\u043d\u044b\u0435 it gels can mimic or testosterone levels in the blood to have a normal physiological smooth testosterone with \u0435\u0436\u0435\u0441\u0443\u0442\u043e\u0447\u043d\u044b\u043c rhythm, the new \u0438\u043d\u0442\u0440\u0430\u043d\u0430\u0437\u0430\u043b\u044c\u043d\u044b\u0435 gels, it is very suitable for substitution or additional tera fdi, testosterone and effective for the treatment of male subjects.have been diagnosed with, for example, the lack of testosterone, in particular low libido, low libido and sexual activity, low fertility low spermatogenesis, \u0430\u0441\u043f\u0435\u0440\u043c\u0430\u0442\u043e\u0433\u0435\u043d\u0435\u0437, depression and \/ or hypogonadism, female subjects with diagnosed, for example, female sexual \u0434\u0438\u0441\u0444\u0443\u043d\u043a\u0446