Herman GRIFFIN,Xiang GAO,Rebecca VELEZ,Wei-Jian PAN
申请号：
US15569338
公开号：
US20180311299A1
申请日:
2016.04.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A method for preventing AMR in a human kidney transplant recipient is provided. The method comprises: selecting a deceased donor selecting a kidney transplant recipient transplanting the kidney from the donor to the recipient and administering a therapeutically effective dose of an anti-C5 antibody or fragment thereof to the recipient. The recipient is generally sensitized to the donor. Also provided is a method for treating AMR in a kidney transplant patient. The method comprises: selecting a kidney transplant patient having symptoms of AMR and administering a therapeutically effective dose of an anti¬ cs antibody or fragment thereof to the patient wherein the dose of anti-C5 antibody or fragment thereof reduces the symptoms of AMR.
