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DISTINCT EFFECTS OF IFN-GAMMA AND IL-17 ON TL1A MODULATED INFLAMMATION AND FIBROSIS
专利权人:
发明人:
David Q. Shih,Stephan R. Targan,Janine Bilsborough
申请号:
US14890699
公开号:
US20160096885A1
申请日:
2014.05.16
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Described herein are methods and compositions related to Inflammatory Bowel Disease. Specifically TL1A drives regional intestinal inflammation and fibrosis and is differentially modulated by IFN gamma and IL-17a. In one embodiment, the present invention is a method of diagnosing a condition in a subject by determining the presence or absence of IFN gamma and/or IL-17 and diagnosing the subject.
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中国工程科技知识中心
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