METHODS AND COMPOSITIONS FOR MODULATING INNATE LYMPHOID CELL PATHOGENIC EFFECTORS

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专利权人:

The Broad Institute, Inc.;Massachusetts Institute of Technology;Yale University

发明人:

Aviv Regev,Piotr Bielecki,Richard Flavell,Monika Kowalczyk,Samantha Riesenfeld,Jan-Christian Huetter,Elena Torlai Triglia

申请号：

US16681050

公开号：

US20200146269A1

申请日:

2019.11.12

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The subject matter disclosed herein is generally directed to methods and compositions for modulating inflammation driven by differentiation of quiescent tissue-resident ILCs into a spectrum of pathogenic effectors. The subject matter disclosed herein is also generally directed to detecting and monitoring an ILC response. Additionally, the subject matter is directed to treating skin inflammation, such as psoriasis.

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http://www.ckcest.cn/home/