The present invention relates to a compound of formula(see formula I)(wherein all symbols have the same meanings as describedhereinbefore). The compound antagonizes cysLT2 andtherefore, it is useful as an agent for the prevention and/ortreatment of respiratory diseases such as bronchial asthma,bronchial asthma, chronic obstructive pulmonary disease,pneumonectasia, chronic bronchitis, pneumonia(e.g.interstitial pneumonitis etc.), severe acute respiratorysyndrome (SARS), acute respiratory distress syndrome (ARDS),allergic rhinitis, sinusitis (e.g. acute sinusitis, chronicsinusitis, etc.), and the like, or as an expectorant orantitussives.