This refers to the compound of the formula (1) or pharmaceutically acceptable salts thereof, and compositions containing the same, processes for preparing the same, method of use, thus Advancing the Hydration of mucosa and the Treatment To diseases, including chronic obstructive pulmonary disease (COPD), Asthma, bronchiectasis,Acute and chronic bronchitis, and emphysema, cystic fibrosis, pneumonia.Jedinjenje sa formulom:ili njegova farmaceutski prihvatljiva so.Prijava sadrži još 15 patentnih zahteva.