abstract of the disclosure the present invention relates compounds of the formula: or pharmaceutically acceptable salts thereof, useful as sodium channel blockers, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including cystic fibrosis, chronic obstructive pulmonary disease, asthma, bronchiectasis, acute and chronic bronchitis, emphysema, and pneumonia. Patent Summary: "3,5-Diamino-6-chloro-n- (n- (4-phenylbutyl) carbamimidoyl) pyrazine-2-carboxamide compounds". The present invention relates to a compound of formula: or pharmaceutically acceptable salts thereof useful as sodium channel blockers, as well as compositions containing the same, processes for preparing it and therapeutic methods of use thereof to promote surface hydration. mucosal diseases, including chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, acute and chronic bronchitis, cystic fibrosis, emphysema and pneumonia.abstract of the disclosure the present invention relates compounds of the formula: or pharmaceutically acceptable salts thereof, useful as sodium channel blockers, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including cystic fibrosis, chronic obstructive pulmonary disease, asthma, bronchiectasis, acute and chronic bronchitis, emphysema, and pneumonia. tradução do resumo resumo patente de invenção: "compostos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil)carbamimidoil) pirazina-2- carboxamida". a presente invenção se refere a um composto de fórmula: ou sais farmaceuticamente aceitáveis do mesmo úteis como bloqueadores do canal de sódio, bem como composições contendo o mesmo, processos para prepare do mesmo e métodos terapêuticos de uso do mesmo para promover a hidrata
