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Genz 112638 polyurethane crystal and amo form, as a mixed inhibitor of glucoacyl cholesterol
专利权人:
GENZYME CORPORATION
发明人:
LIU, Hanlan,WILLIS, Chris,BHARDWAJ, Renu,COPELAND, Diane P.,MARSHALL, John,HARIANAWALA, Abizer,SKELL, Jeffrey,KOCHLING, Jianmei,PALACE, Gerard,PETERSCHMITT, Judith,SIEGEL, Craig,CHENG, Seng
申请号:
PE2016002590
公开号:
PE20171255A1
申请日:
2010.11.24
申请国别(地区):
PE
年份:
2017
代理人:
摘要:
It refers to the sponge salt (I) of genz 112638,Salt is an amoxic salt. At least 70% of the salt by weight is crystalline. The peak value of X-ray dust in eel 2 theta is 5.1 degrees,6.6 degrees10.7°11.0°15.9°,21.7°。 He also mentioned a pharmacologist who could understand her The compound can inhibit the glucose mixed enzyme or reduce the concentration of glycerin, which is an effective method for the treatment of Gaucher's disease.Se refiere a la sal de hemitrartrato de Genz 112638 de formula (I), en donde la sal es una sal amorfa con al menos 70% en peso de sal que es cristalina, donde los picos de difraccion de polvo de rayos X en los angulos 2 theta son 5,1°, 6,6°, 10,7° 11,0° 15,9° y 21,7°. Tambien se refiere a una composicion farmaceutica que la comprende. Dicho compuesto inhibe la glucosilceramida sintasa o reduce las concentraciones de glicoesfingolipidos siendo util en el tratamiento de la enfermedad de Gaucher
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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