Described is an apparatus for calibrating or measuring target points (1) for cerebral neuro-navigators, comprising a processor (2) comprising a video output (3) on which can be displayed a preloaded three-dimensional or two-dimensional map (4) of a brain of a patient, a rigid body (5) comprising a plurality of optical markers (6) and a supporting tip (7) designed to be rested on the head of the patient and a stereoscopic video camera (8) configured to detect a position of the optical markers (6) relative to the head of the patient at a preset point (9) of the head of the patient and sending the position to the processor (2) to allow the acquisition of the preset point (9). The stereoscopic video camera (8) is configured for detecting and sending to the processor (2) static positions and movements of the optical markers (6). The processor (2) is also configured for acquiring the position of the preset point (9) when the movements of the optical markers (6) fall within a preset range of movement (10) for the entire duration of a preset time interval (11).