According to various embodiments, the present disclosure provides a method of imaging reconstruction. The method of imaging reconstruction includes providing a target object, a detector, and a mask disposed between the target object and the detector； acquiring a measured image of the target object by the detector； providing an estimated image of the target object； partitioning the mask into multiple regions； for each of the regions, deriving a forward projection from the estimated image of the target object and the respective region, thereby acquiring multiple forward projections； comparing the measured image of the target object with the forward projections； and updating the estimated image of the target object based on a result of the comparing.
