CAO YU,HACKL WOLFGANG,LI PING,LI SHOUFENG,MIRZA TAHSEEN,ZEHENDER HARTMUT,ZHU JIAHAO
申请号：
NZ61046711
公开号：
NZ610467A
申请日:
2011.12.01
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Provided is an oral pharmaceutical composition comprising an imidazoquinoline derivative compound of the general formula (I), wherein the variables are defined in the specification, Vitamin E TPGS and polyethylene glycol or polyethylene oxide. A preferred compound in the composition is 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile or 8-(6-methoxy-pyridin-3-yl)-3-methyl-1-(4-piperazin-1-yl-3-trifluoromethyl-phenyl)-1,3-dihydro-imidazo[4,5-c]quinolin-2-one. Further provided are processes for making the compositions, a kit comprising the composition and instructions for its use and related uses of the compositions. The compositions are useful in the treatment of cancer.
