Michael Patrick Dillon;Ronald Charles Hawley;Li Chen;Minmin Yang;Lichun Feng
发明人:
Michael Patrick Dillon,Ronald Charles Hawley,Li Chen,Lichun Feng,Minmin Yang
申请号：
US13462115
公开号：
US20120214789A1
申请日:
2012.05.02
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Compounds of the formula I:or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted tetrazolyl, R2 is optionally substituted phenyl, optionally substituted pyridinyl or optionally substituted thienyl, and R3, R4, R5 and R6 are as defined herein. Also provided are methods of using the compounds for treating diseases associated with the P2X3 and/or a P2X2/3 receptor antagonist and methods of making the compounds.
