Li Chen,Michael Patrick Dillon,Lichun Feng,Ronald Charles Hawley,Minmin Yang
申请号：
US14459143
公开号：
US09512089B2
申请日:
2014.08.13
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Compounds of the formula I:or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted tetrazolyl, R2 is optionally substituted phenyl, optionally substituted pyridinyl or optionally substituted thienyl, and R3, R4, R5, R6 R7 and R8 are as defined herein. Also provided are methods of using the compounds for treating diseases associated with the P2X3 and/or a P2X2/3 receptor antagonist and methods of making the compounds.
