Use of an anti-Tau pS422 antibody for the treatment of brain diseases

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专利权人:

Hoffmann-La Roche Inc.

发明人:

Bernd Bohrmann,Ulrich Goepfert,Fiona Grueninger,Walter Huber,Hans-Willi Krell,Valeria Lifke,Olaf Mundigl,Sonja Offner,Laurence Ozmen,Michael Schraemi

申请号：

US13911991

公开号：

US09290567B2

申请日:

2013.06.06

申请国别(地区):

US

年份:

2016

代理人:

摘要：

An antibody binding to Tau that is phosphorylated at serine 422 (pS422), which specifically binds to phosphorylated Tau fragment of SEQ ID NO:9 and to Tau pS422, but does not bind to Tau and to phosphorylated MCAK fragment of SEQ ID NO:17. The antibody is useful in the treatment of a Tauopathy.

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