Richie Khanna,Kenneth Joseph Valenzano,Susan Elizabeth Fowles
申请号:
US14415155
公开号:
US20150174214A1
申请日:
2013.07.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present application provides for compositions comprising α-galactosidase A in combination with an active site-specific chaperone for the α-galactosidase A, and methods for treating Fabry disease in a subject in need thereof, that includes a method of administering to the subject such compositions. The present application also provides methods for increasing the in vitro and in vivo stability of an α-galactosidase A enzyme formulation.