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Alpha-Galactosidase A And 1-Deoxygalactonojirimycin Co-Formulation
专利权人:
发明人:
Richie Khanna,Kenneth Valenzano,Susan Elizabeth Fowles
申请号:
US15639290
公开号:
US20170360901A1
申请日:
2017.06.30
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present application provides for compositions comprising α-galactosidase A in combination with an active site-specific chaperone for the α-galactosidase A, and methods for treating Fabry disease in a subject in need thereof, that includes a method of administering to the subject such compositions. The present application also provides methods for increasing the in vitro and in vivo stability of an α-galactosidase A enzyme formulation.
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