Disclosed is a method for preventing a reduction in feed intake in a non-human animal which occurs when said animal is administered a virginiamycin antibiotic, said method comprising administering to said animal in need of prevention of a reduction in feed intake, increasing doses of a composition comprising the virginiamycin antibiotic over a specified time period. Also disclosed is a method for treating laminitis, fermentative acidosis, equine grass sickness and pulpy kidney in a non-human animal comprising administering to said animal, increasing doses of a composition comprising a virginiamycin antibiotic over a specified time period.