REYNOLDS, ERIC CHARLES,O'BRIEN SIMPSON, NEIL MARTIN,SLAKESKI, NADA,CROSS, KEITH J,OBRIEN SIMPSON, NEIL MARTIN
申请号：
NZ59883409
公开号：
NZ598834A
申请日:
2009.08.28
申请国别(地区):
NZ
年份:
2013
代理人:
摘要：
598834 Prevention, treatment and diagnosis of P. gingivalis infection Provided is a chimeric or fusion protein for inducing an immune response to P. gingivalis comprising a first peptide of about 5 to about 40 amino acids joined directly or through a linker to a second polypeptide, wherein said first peptide comprises a region of a P. gingivalis trypsin-like enzyme with a specified sequence (KAS4, KAS5, or KAS6)； and (ii) part or all of a sequence that is the same as or at least 90% identical to the sequence RAS4 or RAS5, wherein said region of said trypsin-like enzyme is capable of inducing an immune response against P. gingivalis.
