SCHATTKA, JAN HENDRIK,MEIER, CHRISTIAN,JUNG, HERBERT,KRACHTUS, HEDI,DEL ROSARIO FERRAND, JESSICA
申请号：
CA2839525
公开号：
CA2839525C
申请日:
2012.06.12
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The invention discloses a gastric resistant pharmaceutical or nutraceutical composition, comprising a core, comprising a pharmaceutical or nutraceutical active ingredient and a gastric resistant coating layer onto the core, wherein the gastric resistant coating layer comprises at least 30 % by weight of a (meth)acrylate copolymer comprising polymerized units of 10 to 40 % by weight of acrylic or methacrylic acid, 10 to 80 % by weight of a C4- to C18-alkyl ester of acrylic or methacrylic acid and optionally 0 to 60 % by weight of another vinylic monomer, whereby the release of the pharmaceutical or nutraceutical active ingredient is not more than 10 % under in-vitro conditions at pH 1.2 after 2 hours in medium according to USP with and without the addition of 20 % (v/v) ethanol.
