Jan Hendrik Schattka;Herbert Jung;Christian Meier;Jessica Del Rosario Ferrand;Hedi Krachtus
发明人:
Jan Hendrik Schattka,Christian Meier,Herbert Jung,Hedi Krachtus,Jessica Del Rosario Ferrand
申请号：
US14114752
公开号：
US09775815B2
申请日:
2012.06.12
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention discloses a gastric resistant pharmaceutical or nutraceutical composition, comprising a core, comprising a pharmaceutical or nutraceutical active ingredient and a gastric resistant coating layer onto the core, wherein the gastric resistant coating layer comprises at least 30% by weight of a (meth)acrylate copolymer comprising polymerized units of 10 to 40% by weight of acrylic or methacrylic acid, 10 to 80% by weight of a C4- to C18-alkyl ester of acrylic or methacrylic acid and optionally 0 to 60% by weight of another vinylic monomer, whereby the release of the pharmaceutical or nutraceutical active ingredient is not more than 10% under in-vitro conditions at pH 1.2 after 2 hours in medium according to USP with and without the addition of 20% (v/v) ethanol.
