GONZALO HERNÁNDEZ HERRERO,VÍCTOR RUBIO ROYO,NEFTALÍ GARCÍA DOMÍNGUEZ,GONZALO CANAL MORI,NICOLAS TESSON,CARME JIMÉNEZ GONZÁLEZ,JORDI DE MIER VINUE
申请号:
PT16797941
公开号:
PT3377478T
申请日:
2016.11.18
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
The invention relates to a cocrystal comprising a) at least a compound of formula (I), and b) at least a cocrystal forming compound selected from an organic molecule, or a solvate thereof. The invention further relates to methods for obtaining said cocrystals and to their use in the treatment and/or prevention of conditions mediated by H 1 histamine receptor, such as allergic disorders or diseases. The invention also relates to a method for increase the aqueous solubility of the above compounds of formula (I).