There is provided a biomedical sensing system and a method for its use. Such a system includes a diagnostic sensor configured to sense a physiological metric of a living subject via contact with the living subject, and to generate a diagnostic signal corresponding to the physiological metric. In addition, the system includes a motion sensor situated proximate the diagnostic sensor and configured to sense a motion corresponding to a motion of the diagnostic sensor during sensing of the physiological metric. The system also includes an analysis unit including a processor, and a memory storing a motion correction module. The processor is configured to receive the diagnostic signal and the motion signal, and to execute the motion correction module from the memory to adaptively filter the diagnostic signal using the motion signal to produce a motion compensated diagnostic signal.
