A physiological monitoring system may select a light signal for determining a physiological parameter. In some embodiments, the monitoring system may select a received light signal for further processing based on a physiological metric such as blood oxygen saturation value, or based on a system metric such as a signal-to-noise ratio. In some embodiments, the system may determine a light drive parameter based on a received signal. For example, the system may select a received light signal for further processing in order to determine a physiological parameter.