A support system for breast irradiation including a turntable for supporting and rotating a patient about a generally vertical rotational axis, a body-leaning support for supporting the patient leaning thereupon throughout rotation of the patient about the vertical rotational axis, and a radiation shield arranged for shielding non-breast anatomy of the patient from stray radiation, wherein the body-leaning support and the radiation shield are separated from each other by a gap in which breasts of the patient are placeable for irradiation by a horizontal radiation beam.