An endoscope includes a first bending portion that is operated and bent, a function portion that is operated to be capable of performing a predetermined function, a grasping portion including a long axis provided to extend from a distal end portion through a proximal end portion, a first rotation body capable of operating the first bending portion, a second rotation body capable of operating the function portion, and an operation portion main body provided at a proximal end side of the grasping portion, with the second rotation body being disposed at a side where a palm of a hand is located when the grasping portion is grasped with the hand, with the second rotation body facing the first rotation body with the long axis therebetween, and a second shaft being located at a proximal end side from a first shaft.