JANSSEN, BERND,BARLOZZARI, TERESA,HAUPT, ANDREAS,ZIERKE, THOMAS DR,KLING, ANDREAS DR
申请号：
HU0004234
公开号：
HU228996B1
申请日:
1998.07.07
申请国别(地区):
HU
年份:
2013
代理人:
摘要：
Compounds of the present invention include cell growth inhibitors which are peptides of Formula I, <；?in-line-formulae description="In-line Formulae" end="lead"?>；A-B-D-E-F-(G)<；SUB>；r<；/SUB>；-(K)<；SUB>；s<；/SUB>；-L, (I)<；?in-line-formulae description="In-line Formulae" end="tail"?>； and acid salts thereof, wherein A, B, D, E, F, G and K are alpha-amino acid residues, and s and r are each, independently, 0 or 1. L is a monovalent radical, such as, for example, an amino group, an N-substituted amino group, a beta-hydroxylamino group, a hydrazido group, an alkoxy group, a thioalkoxy group, an aminoxy group, or an oximato group. The present invention also includes a method for treating cancer in a mammal, such as a human, comprising administering to the mammal an effective amount of a compound of Formula I in a pharmaceutically acceptable composition.
