John B. Patterson,David G. Lonergan,Gary A. Flynn,Qingping Zeng,Peter V. Pallai
申请号:
US15356292
公开号:
US09981901B2
申请日:
2016.11.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.