Peter V. Pallai;Gary A. Flynn;Qingping Zeng;John Bruce Patterson;David Gregory Lonergan
发明人:
John Bruce Patterson,David Gregory Lonergan,Gary A. Flynn,Qingping Zeng,Peter V. Pallai
申请号：
US12941530
公开号：
US08614253B2
申请日:
2010.11.08
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
