PROCEDE DE FIXATION DE MOLECULES EFECTRICES SUR DES PROTEINES

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专利权人:

UCB PHARMA S.A.

发明人:

HEYWOOD, SAM PHILIP

申请号：

CA2613481

公开号：

CA2613481C

申请日:

2006.06.29

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

The present invention provides a process for attaching one or more effectormolecules to one or more cysteines in a protein comprising: a) activating oneor more cysteines in the protein by diafiltering the protein against amonothiol reducing agent or a multi-thiol reducing agent which is incapable offorming intramolecular disulphide bonds and b) reacting the treated proteinwith an effector molecule.

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