John Martin Brown,Lawrence Recht,Seema Nagpal,Reena Thomas
申请号:
US15997387
公开号:
US20180344690A1
申请日:
2018.06.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods of treatment and pharmaceutical formulation configured to improve the cure rate of patients with solid tumors when treated with radiotherapy are provided. The methods and treatments use an inhibitor of the CXCL12/CXCR4 pathway. The inhibitors prevent the formation of new blood vessels into a tumor that is being treated with radiotherapy. The inhibitor may be continuously infused intravenously towards the end of radiotherapy and continuing thereafter.