Interlocking device (1) for a stopper (100) on a container (101) with a neck (102), said interlocking device (1) comprising a cover (2) provided with at least one internal groove (22) and which is shaped to covering said stopper (100) and surrounding said neck (102) so as to make said stopper (100) inaccessible, a sleeve (4) apt to lodge in said cover (2) and provided with lower internal notches (42) intended to rest under said neck (102) to secure said sleeve (4) with said container (101) and with external notches (44) capable of cooperating with said slot (22) to secure said sleeve (4) with said cover (2), characterized in that said cover (2) comprises at least one frangible zone (Z2) capable of breaking to allow the opening of said cover (2) and its removal with respect to said neck (102) and because said sleeve (4) is formed by a ring (40) prolonged by pins (41) intended to surround said plug (100) and provided with at least one deformable and divisible bridge (45) provided on the opposite side of said pins (41) and suitable, on the one hand, to allow the sleeve (4) to be deformed radially in an elastic way to allowing the forced passage of said neck (102) into said sleeve (4) and, on the other hand, to break to allow the removal of said sleeve (4) with respect to said neck (102) and then the removal of said plug ( 100) of said container (101).Dispositivo de enclavamiento (1) de tapón (100) sobre recipiente (101) con gollete (102), comprendiendo dicho dispositivo de enclavamiento (1) una cubierta (2) provista de al menos una ranura (22) interior y que está conformada para recubrir dicho tapón (100) y rodear dicho gollete (102) de modo que haga dicho tapón (100) inaccesible, un manguito (4) apto para alojarse en dicha cubierta (2) y provisto de muescas internas inferiores (42) destinadas a apoyarse bajo dicho gollete (102) para solidarizar dicho manguito (4) con dicho recipiente (101) y de muescas externas (44) aptas para cooperar con dicha ranura (22) para solid