System of the present invention closes the benzimidazole of what formula 1 and is to close the medical composition that includes the grade compounds, and further the intermediate of what formula 2 and 3 is closed in system.本發明係關於式1之苯并咪唑且係關於包含該等化合物之醫藥組合物,進一步係關於式2與3之中間體。