ガンの中性子捕捉療法を可能とする架橋型ホウ素内包ミセル
- 专利权人:
- 国立大学法人;筑波大学
- 发明人:
- 長崎 幸夫,角谷 省吾,大石 基
- 申请号：
- JP2009217359
- 公开号：
- JP5522361B2
- 申请日:
- 2009.09.18
- 申请国别(地区):
- JP
- 年份:
- 2014
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide a polymer conjugate of a boron compound and a hydrophilic/hydrophobic type block copolymer existing as a stable polymer micelle in a biological environment.
SOLUTION: This polymer conjugate includes at least a structure in which a molecule of a boron compound is crosslinked with two molecules of hydrophilic/hydrophobic type block copolymers via a covalent bond, and the boron compound is bifunctional having two polymerizable functional groups and the hydrophilic/hydrophobic type block copolymer has a polymerizable functional group on the end of its hydrophobic block, and the covalent bond is formed by mutual polymerization reaction of the polymerizable functional group of the boron compound and the polymerizable functional group of the block copolymer. The boron compound is represented by figured formula, wherein the black circle represents BH, L
3 represents a methylene bond or the like and Z represents a polymerizable functional group.COPYRIGHT: (C)2011,JPO&INPIT
- 来源网站：
- 中国工程科技知识中心
