POPPLEWELL, ANDREW GEORGE,CHAPMAN, ANDREW PAUL,KING, DAVID JOHN,ATHWAL, DILJEET SINGH,BROWN, DEREK THOMAS,WEIR, ANDREW NEIL CHARLES
申请号：
DK09176251
公开号：
DK2230308T3
申请日:
2001.06.05
申请国别(地区):
DK
年份:
2013
代理人:
摘要：
There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNF±. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNF±.
