Antibody molecules having specificity for human tumor necrosis factor alpha and use thereof

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专利权人:

UCB PHARMA

发明人:

ATHWAL DILJEET SINGH,BROWN DEREK THOMAS,WEIR ANDREW NEIL CHARLES,POPPLEWELL ANDREW GEORGE,CHAPMAN ANDREW PAUL,KING DAVID JOHN

申请号：

HU1600016

公开号：

HU230553B1

申请日:

2001.06.05

申请国别(地区):

HU

年份:

2016

代理人:

摘要：

There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNF±. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNF±.

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中国工程科技知识中心

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