Regarding this bill, the chemical compound formula (i) or the salt and the solvent dishes dressed with sauce which on the medicine manufacture are allowed, the salt of the professional drag and the professional drag or those combinations (as for R, R, R, R and m with bill it is defined.)Is disclosed. Also remedy manner of the constituent and that kind of chemical compound and use the constituent state and the fault which include that kind of chemical compound is disclosed.本明細書においては、式(I)の化合物または製薬上許容される塩、溶媒和物、プロドラッグ、プロドラッグの塩またはそれらの組み合わせ(R1、R2、R3、R4およびmは明細書で定義されている。)が開示される。そのような化合物を含む組成物ならびにそのような化合物および組成物を用いる状態および障害の治療方法も開示される。