This invention, the chemical compound formula (i) like hidorokishichirosoru or the salt and the solvent dishes dressed with sauce which on that medicine it can allow, includes with the professional drag or isomer and the substrate which on the medicine it can allow, the Characteristic infection symptom like the local medicine constituent, and the HIV infection which possess the value to which R, R and R in formula (i) differ (STD) deals with the use of aforementioned chemical compound as the medicine in preventing.本発明は、ヒドロキシチロソールのような式(I)の化合物又はその医薬上許容し得る塩、溶媒和物、プロドラッグ若しくは異性体と、医薬上許容し得る担体とを含み、式(I)中のR1、R2及びR3が異なる値を有する局所医薬組成物、及びHIV感染のような性感染症(STD)の予防における薬剤としての前記化合物の使用を対象とする。
