Hendrik Jan Houthoff,Augustinus A.M.S. Van Dongen,Robbert Jan Kok,Dennis Christian Johannes Waalboer,Sytze Jan Buwalda,Niels Jurriaan Sijbrandi
申请号:
US14370742
公开号:
US20140377174A1
申请日:
2013.01.04
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A first aspect of the disclosure relates to a method for preparing cell-targeting conjugates by coupling at least one functional moiety, such as a therapeutic compound, diagnostic compound or chelating agent to a targeting moiety. A second aspect of this disclosure relates to the cell-targeting conjugates obtainable with this method. A third aspect of the disclosure described herein relates to pharmaceutical compositions comprising the cell-targeting conjugates.