A thrombus removal means (10) and a thrombus removal device (1) particularly suited to the removal of a thrombus from an intracranial vessel. The thrombus removal means (10) is a mesh structure defining a lumen and is switchable between a contracted configuration and an expanded configuration, the thrombus removal means (10) has inwardly and/or outwardly projecting features. The thrombus removal means (10) can hold a captured thrombus firmly during the retrieval, effectively trap plaques and clot fragments with an improved stiffness and with no possibility for them to dislodge therefrom, and can addresses the issue of distal re-embolization caused by the vessel wall plaques or clot fragments dislodging from the conventional thrombus removal devices by presenting an improved thrombus removal system with the additional benefit of a small profile and high flexibility.