A brassiere incorporating a hot flash mitigation system for cooling the upper torso, chest and neck area of a wearer is disclosed. The brassiere comprises two front panel sections connectively engaged to each other, at least one rear panel section connectively engaged to each of the two front panel sections. The hot flash mitigation system provides a deformable reservoir for containing and dispensing a fluid therefrom. The deformable reservoir is disposed in mating and contacting engagement with the brassiere and has an outlet in cooperative fluid engagement thereto. At least one duct disposed proximate to one of the at least two front panel sections is in fluid engagement with the outlet of the deformable reservoir. At least one nozzle disposed upon an end of the duct distal from the deformable reservoir operatively conveys the fluid from the duct to the upper torso, chest and neck area of the wearer.