#$%^&*AU2018201307A120180315.pdf#####ABSTRACT Formulations comprising a neuroactive steroid, e.g., allopregnanolone; and optionally a cyclodextrin, e.g., a -cyclodextrin, e.g., a sulfo butyl ether P-cyclodextrin, e.g., a p-cyclodextrin, e.g., a sulfo butyl ether P-cyclodextrin, e.g., CAPTISOL@; and methods of use in treating CNS disorders.