#$%^&*AU2020217402A120200903.pdf#####ABSTRACT Formulations comprising a neuroactive steroid, e.g., allopregnanolone; and optionally a cyclodextrin, e.g., a p-cyclodextrin, e.g., a sulfo butyl ether p-cyclodextrin, e.g., CAPTISOL@; and methods of use in treating CNS disorders.